After menopause women obtain most of their circulating estrogrn from the peripheral aromatization of adrenal and ovarian androgens.The ovaries of menopausal women continue to be important sources of androgen production﹑as demonstrated by comparison with women who have had oophorectomy and experience a dramatic decline un circulating androgens.11compared with several years for natural menopause﹑bilateral oophrectomy has shown a dramatic drop in circulating estrogens and testosterone levels （＜10 pg/ml and 5 ng/dl﹑respectively）within 24 to 48 hours after surgery .13﹑14Associated with these abrupt and significantly reduced hormonal levels﹑menopauesal symptoms in surgically menopausal women are generally much more severe than those associated with natural menopause . 3
Although prevalence and severity of symptoms differ significantly﹑the sudden decrease in ovarian hormones commonly results in dramatic symptoms﹑predominately vasomotor instability （e.g. ﹑hot flashes﹑increased perspiration﹑night sweats﹑and insomnia）﹑decreased libido﹑and a lessened feeling of general well-being .7Furthermore﹑more wonen who had surgical menopause reported climacteral symptoms and more severely intensive vasomotor instability than wonen experiencing natural menopause.fatigue﹑short-term memory deficits﹑andsexual function﹑including urogenital atrophic changes﹑are also identified as problematic areas.6Sexual dysfunctional estrogen.Symptoms of urogenital atrophy are clearly estrogen mediated: vaginal dryness, duspareunia, discharge from atrophic vaginitis, dysuria, and other irritating symptoms.15
後3行少ㄌㄧ段6 Sexual dysfunctional after menopause or hysterectomy has been classically attributed solely to the functional estrogen.
- 1 0 年前最佳解答
更年期的婦女從腎上腺及卵巢得到最多動情愫..停經後婦女的卵巢仍是分泌性腺激素的重要來源.舉例說明..一個婦人已經做了卵巢切除手術並且體內的性腺激素就戲劇性的下降..與自然停經了幾年來比較...做了2邊卵巢切除手術不用24-48小時的時間..動情素及睪丸素都立即下降(分別是＜10 pg/ml 和 5 ng/dl)13.14與這些突然又顯著的下降的激素相關..因手術而停經的婦女其停經症候群比自然停經的婦女還要嚴重