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Antioxidant activities of extracts from five anti-viral medicinal plants

Keli Chena,b, Geoff W. Plumba, Richard N. Bennetta, Yongping Baoa,∗

Abstract

The antioxidant activities of five medicinal plants (Ampelopsis sinica, Ampelopsis humiliforlia var. heterophylla, Potentilla freyniana,

Selaginella labordei and Chrysanthemum multiflorum), used in the Hubei province of China, have been investigated using both enzymatic and

non-enzymatic in vitro antioxidant assays. Extracts from all five of the plants inhibited xanthine oxidase and lipoxygenase activities, and were

scavengers of the ABTS•+ radical cation using the Trolox equivalent antioxidant capacity assay (TEAC). Extracts from Potentilla freyniana

and Selaginella labordei down-regulated cyclooxygenase-2 gene expression, measured by real-time RT-PCR, in human colon adenocarcinoma

CaCo-2 cells.

© 2004 Elsevier Ireland Ltd. All rights reserved.

Keywords: Medicinal herb; TEAC; Xanthine oxidase; Lipoxygenase; Cyclooxygenase-2; CaCo-2

1. Introduction

China has a long history of using herbs for the treatment

of human diseases. Potentilla freyniana Bornm. (from

Rosaceae), Selaginella labordei Hieron (from Selaginellaceae),

Chrysanthemum multiflorum Ramat. (from Compositae),

Ampelopsis sinica (Miq.)W.T.Wang and Ampelopsis

humiliforlia Beg var. heterophylla (Thunb.) K. Koch.

(fromVitaceae) are medicinal plants mainly used in the Hubei

province for the treatment of some viral diseases. Of the

five plants, only the Chrysanthemum multiflorum is recorded

in the Chinese Pharmacopoeia (2000). It is a mild-acting

medicine possessing anti-microbial and anti-viral properties

and showing the mildest anti-oxidation activity.

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    以下參考

    來自5 座反病毒的藥用的工廠的選段的抗氧化的活動

    Keli Chena,b,傑夫W。 Plumba,理查N. Bennetta,Yongping Baoa,*

    摘要

    5 棵藥用的植物的抗氧化的活動(Ampelopsis sinica,Ampelopsis humiliforlia 變量。 heterophylla,Potentilla freyniana,

    Selaginella labordei 和菊花multiflorum) ,在湖北省的中國內使用,被調查使用兩個酵催和

    在試管內的非酵催是抗氧化的分析。 從全部抑制xanthine oxidase 和lipoxygenase 活動的植物5 中抽提,是

    使用Trolox的阿布特+基本的陽離子的撿破爛的人相等的抗氧化的能力分析(TEAC) . 從Potentilla freyniana中抽提

    Selaginella labordei抑制對刺激的回應cyclooxygenase-2基因表示,被實時RT-PCR 測量,在人冒號adenocarcinoma

    CaCo-2小屋。

    &-#169;2004 Elsevier愛爾蘭有限公司 版權所有。

    關鍵字︰ 藥草; TEAC; Xanthine oxidase; Lipoxygenase; Cyclooxygenase-2; CaCo-2

    1. 介紹

    中國有一個把藥草用於處理的悠久的歷史

    人疾病。 Potentilla freyniana Bornm。 (從

    Rosaceae) ,Selaginella labordei Hieron(從Selaginellaceae) ,

    菊花multiflorum Ramat。 (從Compositae) ,

    Ampelopsis sinica(Miq.) W.T.Wang和Ampelopsis

    humiliforlia懇求變量。 heterophylla(Thunb.) K。 科克。

    (fromVitaceae) 藥用的植物被主要在湖北使用嗎

    治療一些病毒性疾病的省。

    5 棵植物,只有菊花multiflorum被記錄

    在漢語藥典裡 ( 2000 ) . 它是溫和作秀

    藥擁有反微生物和反病毒的特性

    並且顯示最溫和的反氧化的活動。

    參考資料: 自己
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