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張西瓜 發問時間: 社會與文化語言 · 1 0 年前

急!煩請醫學翻譯 - 英翻中

Non-classical major histocompatibility complex proteins as determinants of tumour immunosurveillance.

Tumours develop in vertebrate organisms endowed with immune systems that are potentially able to eradicate them. Nevertheless, our ever-increasing understanding of the complex interactions between lymphocytes and tumour cells fuels the long-standing hope of developing efficient immunotherapies against cancer. This review focuses on a versatile family of proteins, the major histocompatibility complex class Ib, which has been recently implicated in both the establishment of anti-tumour immune responses and in tumour immune response evasion. We focus on a subset of class Ib proteins, human leukocyte antigen (HLA)-G, Qa-2, CD1d and NKG2D ligands, which bind to either stimulatory or inhibitory receptors expressed on T, natural killer (NK) and NKT lymphocytes, and thereby modulate their anti-tumour activity.

煩請簡單告訴我重點在哪

大概在說些什麼

不要翻譯軟體 謝謝喔:)

1 個解答

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  • 1 0 年前
    最佳解答

    作為immunosurveillance 瘤的決定原素的非古典主要的histocompatibility複雜的蛋白質。

    瘤在具有潛在能根除他們的免疫的系統的脊椎動物生物體裡發展。 雖然如此,我們的不斷增加的理解在淋巴細胞和瘤細胞燃料之間的複雜的相互作用預防癌症發展有效率的免疫療法的長期的希望。 這篇回顧集中于一個蛋白質的多才多藝的家庭, 在同書的主要的histocompatibility複雜的種類,最近和兩個建立反瘤的免疫的回應有牽連並且在瘤免疫的回應逃避裡。 我們在同書集中于一個種類的子集蛋白質, 人白細胞抗原(HLA)-G,Qa-2,CD1d和NKG2D ligands,對在T上表示的stimulatory或者禁止的感受器捆, 天生的兇手(NK)和NKT 淋巴細胞,而且因此調節他們的反瘤的活動。

    參考資料: 人白細胞抗原(HLA)-G,Qa-2,CD1d和NKG2D ligands,對在T上表示的stimulatory或者禁止的感受器捆, 天生的兇手(NK)和NKT 淋巴細胞,而且因此調節他們的反瘤的活動。
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