川o.川 發問時間: 社會與文化語言 · 1 0 年前

生物paper翻譯

想請高手幫我翻譯這篇文章

Model cell lines are essential tools for investigating the biology and therapeutics of cancer. Approximately 1500 human hematopoietic neoplastic cell lines have been described, covering most major disease entities. Waldenström's macroglobulinemia (WM) is a rare incurable hematological neoplasm from which only three cell lines have been derived. Mindful that candidate tumor cell lines sometimes arise spuriously by viral immortalization of bystander cells, we review the extent to which WM cell lines portray established disease features in vitro. At closer inspection, it seems that none convincingly displays morphological, immunophenotypic, genotypic or biological features characteristic of WM. Rather it appears that two cell lines (WM1 and BCWM.1) are most probably Epstein-Barr virus-immortalized B-lymphoblastoid cell lines, derived from bystander B-cells. The third cell line (WSU-WM) carries the most common cytogenetic hallmark of Burkitt lymphoma, namely t(8;14)(q24;q32), while none have been shown to carry chromosome 6 deletions recently demonstrated as indicative of disease progression in this entity. In summary, although three WM cell lines are currently used as in vitro models, none convincingly pass muster.

謝謝

已更新項目:

hematopoietic

Waldenström

macroglobulinemia (WM)

immortalization

immunophenotypic

(WM1和BCWM.1)

Epstein-Barr

Blymphoblastoid

(WSU-WM)

Burkitt

有人可以補充這些單字嗎?

2 個解答

評分
  • 1 0 年前
    最佳解答

    這段話的意思是:

    式樣細胞系是為調查癌症生物和治療學的根本工具。 大約1500人的hematopoietic造形術細胞系被描述了,包括多數主要疾病個體。 Waldenström的macroglobulinemia (WM)是仅三細胞系獲得了的一個罕見的無可救藥的血液學瘤。 記住候選人腫瘤細胞系由的外人細胞的病毒immortalization假地有時出現,我們回顧WM細胞系刻畫建立的疾病特點體外的程度。 在結束檢查,看起來什么都不令人信服地顯示形態, immunophenotypic,基因型或者生物特點典型WM。 寧可看起來二細胞系(WM1和BCWM.1)大概是Epstein-Barr病毒不朽的Blymphoblastoid細胞系,獲得從外人B細胞。 第三細胞系(WSU-WM)運載最共同的細胞遺傳的標記Burkitt淋巴瘤,即t (8; 14) (q24; q32),而什么都在這個體未顯示運載染色體6個刪除最近被展示如表示疾病進步。 總之,雖然三WM細胞系當前使用作為體外模型,什么都不令人信服地通過集合。

  • 1 0 年前

    補充這些單字的意思是~

    你很滿意回答一的翻譯囉?

    看來又是一個翻譯軟體也可的發問者

    不必我費心追蹤了。。。

還有問題?馬上發問,尋求解答。