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[英文]請幫我翻譯一下這段文章(急)

Abstract

cdc25C is a phosphatase which regulates the activity of the mitosis promoting factor cyclin B/cdk1 by dephosphorylation, thus triggering

G2/M transition. The activity of cdc25C is regulated by phosphorylation which by itself is implicated in regulating the subcellular

localization. It is well accepted that cdc25C has to enter the nucleus to activate the cyclin B/cdk1 complex at G2/M transition. Here, we

will show that cdc25C is located in the cytoplasm at defined dense structures which by immunofluorescence analysis as well as by biochemical

subfractionation turned out to be the Golgi apparatus. It will be further shown that cdc25C at the Golgi fraction is an active

phosphatase suggesting an additional and new role of cdc25C at the Golgi apparatus.

2 個解答

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  • 小k
    Lv 4
    1 0 年前
    最佳解答

    Abstract 摘要

    cdc25C is a phosphatase which regulates the activity of the mitosis promoting factor cyclin B/cdk1 by dephosphorylation, thus triggering G2/M transition.

    cdc25c是一種磷酸酯酶, 能夠藉由去磷酸化去調節細胞有絲分裂的激活力,促進cyclin b/cdk1的分解,進而促使G2/M的進程。

    The activity of cdc25C is regulated by phosphorylation which by itself is implicated in regulating the subcellular localization.

    磷酸化作用抑制了CDC25C活性,也連帶影響了微細胞的定位。

    It is well accepted that cdc25C has to enter the nucleus to activate the cyclin B/cdk1 complex at G2/M transition.

    無可否認,cdc25c能在G2/M週期時,進入細胞核去激活cylinb/cdk1的複合。

    Here, we will show that cdc25C is located in the cytoplasm at defined dense structures which by immunofluorescence analysis as well as by biochemical subfractionation turned out to be the Golgi apparatus.

    在此,我們可以指出cdc25c是位於一個明確且緻密細胞質結構裡,並且藉由免疫螢光分析以及精餾法,可以證明這個結構就是高基氏體。

    It will be further shown that cdc25C at the Golgi fraction is an active phosphatase suggesting an additional and new role of cdc25C at the Golgi apparatus.

    更進一步顯示,cdc252在高基氏體的影響下就成為一種活化的磷酸酯酶,也重新定義了cdc25c在高基氏體上扮演的(額外的)新角色。

    參考資料: me + 網路
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  • ponpon
    Lv 5
    1 0 年前

    Abstract

    *摘要

    cdc25C is a phosphatase which regulates the activity of the mitosis promoting factor cyclin B/cdk1 by dephosphorylation, thus triggering G2/M transition.

    *cdc 25個 C 是管理促進 dephosphorylation 的因素 cyclin B/cdk 1 的有絲分裂的活動的 phosphatase,如此觸發G2/M 轉變。

    The activity of cdc25C is regulated by phosphorylation which by itself is implicated in regulating the subcellular localization.

    *cdc 的活動 25個 C 被獨自在管理子格狀自動化方面被產生關係的 phosphorylation 管理本土化。

    It is well accepted that cdc25C has to enter the nucleus to activate the cyclin B/cdk1 complex at G2/M transition.

    *它被充份接受, cdc 25個 C 必須進入核心在 G2/M 轉變刺激 cyclin B/cdk 1個合成物。

    Here, we will show that cdc25C is located in the cytoplasm at defined dense structures which by immunofluorescence analysis as well as by biochemical subfractionation turned out to be the Golgi apparatus.

    *在這裡,我們將顯示 cdc 25個 C 在定義密集的結構位於細胞質藉著 immunofluorescence 分析和被生物化學的

    被變成 Golgi 裝置的子分別。

    It will be further shown that cdc25C at the Golgi fraction is an active phosphatase suggesting an additional and new role of cdc25C at the Golgi apparatus.

    *它將更進一步被顯示 cdc 25個 C 在 Golgi 分數是一積極的phosphatase 在 Golgi 裝置建議一個 cdc 的另外和新角色 25個 C。

    參考資料: yahoo
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