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匿名使用者
匿名使用者 發問時間: 社會與文化語言 · 1 0 年前

有關脂質過氧化文獻看得懂的大大幫幫我吧~請幫我解釋一下感恩!

我已經有用翻譯軟體翻譯一次了

但是我的英文不是很好~翻得很不順

請各位英文不錯的大大或是看的懂這篇英文文獻的大大們

麻煩幫幫我一下

有點急

拜託拜託

萬分感激

以下是原文

The aim of this study was to investigate the effect of the changes of taurine levels

in the hearts of old rats on endogenous malondialdehyde (MDA) and diene conjugate

(DC) levels and ascorbic acid (AA)- and NADPH-induced lipid peroxidation as well as nonenzymatic

(glutathione, vitamin E and vitamin C) and enzymatic antioxidants (superoxide

dismutase, glutathione peroxidase and glutathione transferase). Two groups of old (22 mo)

rats were treated with

-alanine (3%, w/v; in drinking water), a taurine depleting agent, or

taurine (2% w/v; in drinking water) for 6 wk. Significant decreases were observed in taurine

contents of hearts in old rats as compared to young (5 mo) rats. We found that MDA and DC

levels and AA- and NADPH-induced lipid peroxidation increased, but non-enzymatic and

enzymatic antioxidants did not alter in heart homogenates of aged rats.

-Alanine administration

resulted in significant decreases in heart taurine levels of old rats. This treatment did

not cause further increases in MDA or DC levels or changes in antioxidants. However, AAand

NADPH-induced lipid peroxidation was higher than that of old rats. Taurine treatment

caused significant increases in heart taurine levels of old rats. This treatment was found to

decrease endogenous MDA and DC levels without affecting the antioxidant system in the

heart homogenates of aged rats. AA- and NADPH-induced lipid peroxidation was also

reduced in old rats when given taurine, although not statistically significantly. Our results

indicate that the changes in heart taurine levels may influence the susceptibility of heart tissue

to lipid peroxidation in aged rats and that taurine supplementation has protective effects

on age-dependent oxidative stress in heart tissue.

補充一下我搞不懂mo是什麼?感謝感謝

1 個解答

評分
  • 1 0 年前
    最佳解答

    這項研究的目的是調查taurine 水準的變化的影響

    在老老鼠的心裡在內生的malondialdehyde(MDA)上 以及diene共軛物

    (DC) 水準和抗壞血酸(AA) -以及NADPH 引起的類脂peroxidation以及nonenzymatic

    (glutathione,維生素E 和維生素C) 並且酵催抗氧化劑(superoxide

    dismutase,glutathione peroxidase 和glutathione transferase) . 兩組老(22次用手操作)

    老鼠被用處理

    -alanine(3%,w/v; 在飲用水方面) ,taurine 耗盡代理人,或者

    taurine(2%的w/v; 在飲用水方面) 對於6 wk來說。 顯著的減少被在taurine方面觀察

    在與年輕的(5次用手操作)相比較老老鼠裡的心的內容 老鼠。 我們找到那MDA 和DC

    水準和AA 和NADPH 引起類脂peroxidation增加,但是非酵催和

    酵催的抗氧化劑沒在心裡改變年老的老鼠的homogenates。

    -Alanine 管理

    導致在心方面的顯著的減少的taurine各級老老鼠。 這種處理方法起作用

    不引起更進一步的MDA或者DC 水準或者在抗氧化劑內的變化的增加。 不過,AAand

    NADPH 引起的類脂peroxidation比老老鼠的高。 Taurine 處理

    引起的顯著的心的增加taurine各級老老鼠。 這次處理被發現

    減少內生MDA 和DC 水準沒有影響那些抗氧化系統在方面

    年老的老鼠的心homogenates。 AA 和NADPH 引起類脂peroxidation也

    當被給taurine,雖然不據統計相當時,在老老鼠裡降低。 我們的結果

    表明那在心方面的變化taurine 水準可以影響心組織的靈敏性

    對在年老的老鼠和那個裡的類脂peroxidation來說taurine 增補有保護效應

    在在心組織裡的依靠年齡的氧化的壓力上。

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