病毒 發問時間: 社會與文化語言 · 1 0 年前

Amyloid Precursor Protein 翻譯段落

麻煩專家們別用翻譯機 感謝

A fourth candidate gene, apolipoprotein E (apoE), has been identified in a study of sporadically occurring cases by using non-parametric linkage analysis of affected pedigree members of a set of 32 families where 87 out of 293 members suffered from AD.

Amyloid Precursor Protein

•Single transmembrane spanning protein

•Encoded by a single gene on chromosome 21

•Three isoforms generated by alternative splicing of exons 7 & 8

•Small region of the extracellular/transmembrane domain contains the short peptide sequence Aß which is the principal component of (and thought to be a major contributor to the generation of) amyloid placques

Aberrant protein processing ot APP leads to formation of a toxic protein product in enough amounts that cause the the neurodegenerative process to accelerate

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  • 1 0 年前
    最佳解答

    在32個有受阿耳滋海默氏病症侵襲的血統家庭中,共293人有87人患病.研究中指出血液中 以非參數連鎖分析出偶發性的第四候選基因 apolipoprotein E (apoE).

    Amyloid Precursor Protein <---澱粉型態的xx蛋白質 不會翻

    以下太多專有名詞 沒唸過的很難懂 我自動放棄 ˇ.ˇ

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