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The correlation between radiosensitivity and the presence of oxygen was made by Petry in 1923 from a study of the effects of radiation on vegetable seeds.All of these results were published in the German literature but were apparently little known in the English-speaking world.

In England in the 1930s, Mottram explored the question of oxygen in detail, basing his investigations on work of Crabtree and Cramer on the survival of tumor irradiated in the presence or absence of oxygen. He also discussed the importance of these findings to radiotherapy. Mottram began a series of experiments that culminated in a quantitative measurement of the oxygen effect by his colleagues Gray and Read, using as a biologic test system the growth inhibition of the primary root of the broad bean.

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  • 老古
    Lv 7
    1 0 年前
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    The correlation between radiosensitivity and the presence of oxygen was made by Petry in 1923 from a study of the effects of radiation on vegetable seeds.All of these results were published in the German literature but were apparently little known in the English-speaking world.

    「放射線感受性」與「氧的存在」有關連性, 這是 Petry 在1923年從一項放射線對疏菜種子效應之研究中發現的。所有相關的結果皆刋於德國文獻中, 但顯然地在英語系國家卻很少人知道。

    In England in the 1930s, Mottram explored the question of oxygen in detail, basing his investigations on work of Crabtree and Cramer on the survival of tumor irradiated in the presence or absence of oxygen. He also discussed the importance of these findings to radiotherapy. Mottram began a series of experiments that culminated in a quantitative measurement of the oxygen effect by his colleagues Gray and Read, using as a biologic test system the growth inhibition of the primary root of the broad bean.

    在30年代的英國, Mottram檢視了Crabtree 和 Cramer「有氧及無氧電療後腫瘤殘存之研究」的相關作業並據此進而對氧的影響作更詳細的探究。這些研究對放射性治療的重要性他也提出了他的論述. Mottram開啟了一系列「測定氧效應」相關的實驗而至他的同事 Gray 和 Read 利用生物檢測系統來測定蠶豆主根成長受抑制的情形時達到最高峰。

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