i i 發問時間: 健康疾病與處置癌症 · 8 年前

幫忙翻譯乳癌的病理報告

由於都是專有名詞,看不懂,非常憂心,請協助翻譯。

DIAGNOSIS:1.invasive ductal carinoma (T2) withregional lymph node metastasis (1/16,N1) left breast,partial mastectomy withlymph node dissection2.Free of,skin and section margins GROSS DESCRIPTION:1.Breast (6.5*4.5*2.3cm and 83 gm) withoverlying skin(5.6*2.3cm)and attached axillary fat2.Tumor size:2.4cm;nearest margindistance:1mm at tumor base3.Nearest distance from lateralmargin:3mm(inferior aspect)4.A separate bottle labeled asthoracodorsal LN:one fragment,2*1*0.3cm Representative sections are labeled as:RA-RB:tumor RC,RD:with section marginsRE-RI: leve I LNAJ:thoracodorsal LN Microscopic description:1. Histological type: invasiveductal carcinoma2. Tumor Size: 2.4cm(gross/microscopic)3. Histologic grade (Nottinghamhistologic score):Grade II/IIIa).Tubules:score=3b).Nuclei: score=2c).Mitoticrate:score=14. Extensive Intraductal Component: absent5. Peritumor lymphatic/vascularinvasion : not identified6. Margin distance :1 mm7. Surgical margins :all marginsgrossly and microscopically free8. Skin :free9. Axillary lymph node status:Metastatic carcinoma(1/16,N1) in level one node.Extracpsular extension :absent; size of the largest metastatic node :0.7mm.The single thoracodorsal node isnegative. Immunohistochemical study:1. Staining for estrogen receptor onsection A is Positive (90%)2. Staining for Progesteronereceptor on section A is Positive (90%)3. Her-2 result : 3+.

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  • 8 年前
    最佳解答

    DIAGNOSIS:1.invasive ductal carinoma (T2) withregional lymph node metastasis (1/16,N1) left breast,partial mastectomy withlymph node dissection2.Free of,skin and section margins

    這一段是代表總結的診斷,病人罹患的是乳癌中的侵犯性腺管癌,占乳癌類性中的百分之七十左右,腫瘤大小屬於國際共同定義的腫瘤分期中的T2(最高為T4),取下的淋巴結一共有16顆,其中有1顆受感染,所以腫瘤分期中的淋巴結程度為N1,所採取的術式是左側乳房部分切除及腋下淋巴結清除

    GROSS DESCRIPTION:1.Breast (6.5*4.5*2.3cm and 83 gm) withoverlying skin(5.6*2.3cm)and attached axillary fat2.Tumor size:2.4cm;nearest margindistance:1mm at tumor base3.Nearest distance from lateralmargin:3mm(inferior aspect)4.A separate bottle labeled asthoracodorsal LN:one fragment,2*1*0.3cm

    這一段代表肉眼可見的腫瘤與切下組織外觀描述,看看就好,重點是在後面

    Microscopic description:1. Histological type: invasiveductal carcinoma2. Tumor Size: 2.4cm(gross/microscopic)3. Histologic grade (Nottinghamhistologic score):Grade II/IIIa).Tubules:score=3b).Nuclei: score=2c).Mitoticrate:score=14. Extensive Intraductal Component: absent5. Peritumor lymphatic/vascularinvasion : not identified6. Margin distance :1 mm7. Surgical margins :all marginsgrossly and microscopically free8. Skin :free9. Axillary lymph node status:Metastatic carcinoma(1/16,N1) in level one node.Extracpsular extension :absent; size of the largest metastatic node :0.7mm.The single thoracodorsal node isnegative.

    這一段在說明腫瘤在顯微鏡下所觀察到的情況,基本上重點在於前面所講到的腫瘤分期,另外也有提到腫瘤切除的邊緣是乾淨的,沒有殘餘癌細胞

    Immunohistochemical study:1. Staining for estrogen receptor onsection A is Positive (90%)2. Staining for Progesteronereceptor on section A is Positive (90%)3. Her-2 result : 3+.

    免疫染色,這三項是關係到乳癌要如何治療的重要決定關鍵,第一個簡稱ER,第二個簡稱PR,第三項則是決定可否健保使用標靶藥物的關鍵,以此個案而言,三者全部為陽性,且Her-2為最強烈的3價,這代表個案的癌細胞屬於活化性較強的,較容易有復發的可能,就這樣看起來,主治醫師應會建議化療、放療並用(最起碼化療是一定要的),之後須再服用荷爾蒙,另外健保的標靶應該可以通過審核(審核的詳細要點請詢問主治醫師,因為國健局的政策常常更改,不曉得我所知道的是否過時了)

    參考資料: 現為醫學中心癌症個案管理師
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